Award Winning Formula
The Dawn of the 21st Century - Probiotics vs Antibiotics
Dr. Ohhira's Study of Human Bacteria
Probiotics: The Good Bacteria
How are Dr. Ohhira's Probiotics made?
The Benefits of Dr. Ohhira's Probiotics
Scientific Research of Dr. Ohhira's Probiotic formula
Additional Information on Dr. Ohhira's Probiotics Formula
Shield yourself from deadly "smart bugs"
Additional Articles on Probiotics
The Probiotic Miracle
As we know, the technological revolution of the 20th century launched discoveries, events and activities that have helped shape the highest standard of living known to mankind. Within the health industry alone, many deadly diseases have been totally eradicated and scientists continue almost daily to announce new breakthroughs that could lead to improved health care. But many challenges to human health still exist.
Today, humans are confronted with a hustle-and-bustle lifestyle unimaginable twenty years ago. While enjoying the highest standard of living ever known to man, humans are dubiously rewarded with increased stress and tension, exposure to life-threatening environmental pollutants, viruses and bacteria previously unknown to scientists. Many of the unintended consequences of the technological revolution adversely affect human health.
For example, antibiotics, one of the wonder drugs of the 20th century, have helped conquer many diseases that previously resulted in death or disablement. We now know, however, that antibiotics have limitations and their, use and misuse has frequently led to ill health.
There also are a number of viruses and bacteria that have developed partial or total resistance to some antibiotics. Further, "wide-spectrum" antibiotics usually don't distinguish between "bad" and "good" bacteria. They kill the good bacteria along with the bad bacteria and this indiscriminate killing of bacteria may be one of the worst side effects of using antibiotics.Dr. Ohhira's Study of Human Bacteria
Iichiroh Ohhira, Ph.D., a renowned microbiologist who studied at Okayama University in Japan, has dedicated his life to the study of human bacteria and how to improve human health by ensuring the presence of adequate colonies of good bacteria in the gastrointestinal tract and elsewhere.
Dr. Ohhira first studied lactic acid producing bacteria in China. There, he observed that many persons lived very long and productive lives. After scrutinizing their eating habits, he discovered that it was mainly the fermented foods they ate that led to their good health and longevity.
In an effort to identify and isolate the beneficial ingredients of the many fermented foods consumed in Asia, Dr. Ohhira researched and studied these foods for decades. As a result of his efforts, and that of his team of research scientists, he concluded, "there are two types of human bacteria--the "good" or friendly types and the "bad" or harmful types." He also confirmed that each human requires approximately 85 percent of the good bacteria to nourish the body and keep it healthy. He further determined that although there are more than 100 kinds of lactic acid bacteria, only about 20 are actually beneficial to human health.
Dr. Ohhira soon learned that the human body, although created with the proper ratio of good to bad bacteria, frequently alters the ratio of bacteria as a result of today's modern lifestyle. The use of antibiotics inhibit not only bad bacteria but also good bacteria, thus permitting bad bacteria to invade the Gl tract and multiply in high numbers sufficient to disturb the delicate balance between the good and bad bacteria. This balance also is upset by the use of oral contraceptives, steroids, exposure to radiation through x-rays and radiation therapy, excessive consumption of chlorinated water, the consumption of refined sugars and other refined foods, poor digestion, poor elimination of waste, stress, an unhealthy diet, etc.
Scientists have determined that when the delicate balance between good and bad bacteria is adversely altered, in favor of the bad bacteria the body is overloaded with toxins and disease. According to the Royal Society of Medicine of Great Britain, toxins emanating from the Gl tract may be the cause of 90 percent of all chronic diseases.
Scientists also have determined that there are many negative health effects that stem from the loss of probiotics (good bacteria) including the lack of re circulation of female hormones such as estrogen, the overgrowth of detrimental, disease-causing bacteria and yeasts such as Clostridium dificile, Candida albicans, Staphylococcus aureus, E. coli, Yersinia enterocolitica, etc.
The presence of too few probiotics encourages the production of endotoxins in the Gl tract, which contributes to lupus erythematosus, pancreatitis, psoriasis and other skin conditions. Further, a shortage of probiotics allows partially digested proteins to enter the bloodstream contributing to eczema, nervous system disorders, rheumatoid arthritis, and a variety of other immune system disorders.
A loss of probiotics and the appearance of the detrimental (bad) bacteria contribute to Gl tract problems such as leaky bowel syndrome, ulcerative colitis, irritable bowel syndrome, etc. Also, specific strains of detrimental bacteria have been proven to cause severe health problems. For example, E. Coli may lead to problems with insulin and blood sugar function. Yersinia enterocolitica, a bad bacterium, produces substances that cause the over-production of the thyroid hormone. This detrimental bacterium, reportedly, contributes to autoimmune diseases.
After more than 20 years of thorough research, Dr. Ohhira has scientifically concluded that good health prevails when good bacteria in the gastrointestinal tract are properly colonized. Ill health is the result of too great a colony of bad bacteria.
Based on Dr. Ohhira's findings, it would then seem to be a logical conclusion that simply providing large numbers of good bacteria to sick and unhealthy persons should lead to dramatic improvement in their unhealthy condition. Right? Wrong!
Dr. Ohhira has found that the consumption and short-term presence of good bacteria alone does not lead to good health unless the digestive tract is totally free from the onslaught of the harmful bacteria. This beneficial condition can only be realized by reconditioning the colonic pH. Simply introducing friendly bacteria in large numbers will not resolve the situation because an unfavorable colonic condition has already been created. Such a condition is conducive to the proliferation of harmful bacteria.
After studying human health for decades, Dr. Ohhira understands the basic foundation of good health and now knows how to alter the micro flora in the colon so humans can ensure a healthy immune system and enjoy good health. He has concluded that an important approach to good health is to remove the harmful bacteria from the colon by creating an exclusive condition (i.e. an acidic pH) that is only conducive for the proliferation of friendly bacteria. He further believes that unless the harmful bacteria are totally eradicated in a natural manner, good health cannot be established and maintained.
The colonization of the friendly bacteria in the Gl tract begins at birth. Dr. Ohhira and other scientists observed that a high percentage of children nourished on mother's milk enjoy good health and a stronger immune system when compared to bottle-fed infants. He also observed that these children acquired a larger number of friendly strains of bifidobacteria when compared to bottle-fed children who had few or none at all. Studies by other scientists tend to confirm that cesarean-section babies frequently have lesser amounts of friendly bacteria than do normal birth babies, and in some instances, these c-section babies lack certain strains of the good bacteria entirely. This finding has led scientists to conclude that certain good bacteria may be introduced to the infant as it passes through the mother's birth canal.Dr. Ohhira also noted that the acidic colon condition of breast-fed babies remained within a constant range of pH 5.5 to 6.5. His studies have established that the lactic acid producing bacteria that colonized the colon of infants created this acidic condition. The organic acids, produced by the lactic acid bacteria present in the colon, prevent the survival of harmful bacteria in the baby's gastrointestinal tract. This condition forms the first line of defense for the baby against any form of illness.
As Dr. Ohhira delved further into the science of good health, he discovered that certain naturally fermented foods consumed in Asia are a rich source of lactic acid bacteria. After years of studying the known strains of lactic acid bacteria occurring in fermented foods indigenous to Southeast Asia, Dr. Ohhira developed an award-winning probiotic formula that re colonizes the micro flora in the digestive tract, enhances the immune system, and promotes good health.
Dr. Ohhira also has found that the excessive use of antibiotics has led to the creation of new strains of "super" bacteria that have become resistant to antibiotics. To combat these new harmful invaders, Dr. Ohhira's team developed a special, transient TH 10 strain of friendly lactic acid bacteria that was successfully isolated from the Malaysian food delicacy--Tempeh. This special TH 10 strain has been found during in vitro studies to be extremely effective against the most potent antibiotic resistant MRSA (methicillin resistant Staphylococcus aureus) super bug.
The transient, combative TH 10 lactic acid bacteria may be the most important strain of bacteria in Dr. Ohhira's Original Probiotic Formula because of its ability to kill and eliminate harmful bacteria found in the colon. It also aids in the removal of toxins produced in the colon by the bad bacteria. After consumption, the TH 10 bacteria reside in the Gl tract for an extended period of time where they flourish and coexist with the "colonizer" bacteria, like the lactobacillus and bifidobacteria strains that inhabit the gastrointestinal walls and aid in digestion and the absorption of nutrients.
Dr. Ohhira's Original Probiotic Formula is made only in Japan using a five-year, natural-environment method of manufacturing. Only superior natural ingredients are used in Dr. Ohhira's Original Probiotic Formula.
The special TH 10 strain of bacteria, as well as the eleven other strains of live lactic acid bacteria, are created during a five-year period that includes a two-year natural fermentation period (during which time superior raw materials are introduced), a two-year "maturation" process, and a one-year period that permits the final modification of Dr. Ohhira's Original Probiotic Formula, all accomplished in a natural temperature environment. During this five-year period, only organic ingredients are used including wild herbs and fruits collected from the cold mountainous Chugoku district of Japan and seaweed carefully harvested from Japan's ocean.
Ingredients include 92 types of natural crops, including special leaves, bark, herbs and fruits, which grow wild in a vast region of the Kibi Highlands and Hiruzen Highlands of the Chugoku district, several kinds of seaweed and various organic vegetables. This proprietary blend is combined with twelve strains of lactic acid bacteria, which include the most prominent strains of bacteria possessing the highest proteolytic power in the world. In fact, scientists have established that the lactic acid bacteria contained in Dr. Ohhira's Original Probiotic Formula are 6.25 times stronger than any naturally occurring lactic acid bacteria.
Major ingredients used in Dr. Ohhira's Original Probiotic Formula include--seven wild fruits: Chinese matrimony (Lychium Chinese), Wild vine (Vitis coignetiae), Chinese bayberry (Myrica rubra), Mulberry (Mows australis), Wild strawberry (Rubus buergeri), and Oleaster (Elaeagnus montana)', two seaweed: Sea tangle (Laminaria japonica) and Brown seaweed (hijikia fusiforme); and two herbs: Mugwort (Artemisia montana) and Broad-leafed plantain (Plantago asciatica).
During the five-year production period, the creation of the four organic acids--acetic, formic, fumaric and lactic---are carefully monitored. Daily inspections are conducted to determine the pH and nutrient levels of the fermentation product and to guard against contamination. Inspections also assure compliance with stringent Japanese good manufacturing practice (GMP) standards. Dr. Ohhira's Original Probiotic Formula is analyzed by the Japan Food Research Laboratories, which is authorized by the Japanese Government. Only when Dr. Ohhira's Original Probiotic Formula accumulates a scientifically preordained level of organic acids is the raw paste ready for encapsulation. The highly regarded Fuji Capsule Company Limited of Japan provides the high-tech encapsulation of Dr. Ohhira's Original Probiotic Formula.
Dr. Ohhira has developed a special outer capsule that permits Dr. Ohhira's Original Probiotic Formula to remain highly viable with a stable shelf life of more than five years when properly handled and stored. Unlike other probiotics, it contains 12 strains of friendly "live" lactic acid bacteria (numbering in the hundreds of millions), vitamins, minerals, amino acids, organic acids and important natural byproducts when it is encapsulated. Dr. Ohhira's Original Probiotic Formula is guaranteed to contain those "listed" nutrients, although the actual levels of vitamins, minerals and amino acids may vary slightly among batches due to the natural variation of ingredients.
This is the story of how lichiroh Ohhira, Ph.D. (with an eminent advisory professor and a team of distinguished research scientists at Okayama University in Japan) researched and developed a high-tech dietary supplement formulated to restore and maintain a healthy immune system and promote good health.
Within every human being is a flourishing, living colony of approximately four pounds of bacteria. Most of these bacteria reside in the human digestive tract although some are found elsewhere (i.e. the oral cavity, throat, etc.). Without a sufficient number of good bacteria, known as probiotics, human life would cease to exist. Consequently, if humans fail to maintain a sufficient number of good bacteria in the body, disease will occur and death likely will follow.
It is extremely important for humans to cultivate and maintain a healthy colony of good bacteria in the gastrointestinal tract, a colony that is composed mainly of several strains of living lactic acid bacteria, ideally, the microflora colony in the digestive tract should be composed of a ratio of 85 percent friendly bacteria to 15 percent harmful bacteria. The regular consumption of a high quality probiotic product that contains numerous strains of living lactic acid producing bacteria will enhance a person's efforts to maintain a healthy micro flora colony of bacteria in the digestive tract.
Antimicrobial Activity Against Methicillin-resistant Staphylococcus aureus in the Culture Broth of Enterococcus faecalis TH 10, an Isolate from Malaysian Fermentation Food-Tempeh.
Authors: I. Ohhira, Ph.D., T. Tamura, Ph.D., N. Fujii, Ph.D., K. Inagaki, Ph.D., and H. Tanaka, Ph.D. Department of Biological Resources, Faculty of Agriculture, Okayama University, Okayama, Japan. Published in the Japanese Journal of Dairy and Food Sciences, Vol. 45, Number 4 (1996).
Antimicrobial Activity Against MRSA
Authors: I. Ohhira, Ph.D., T. Tamura, Ph.D., N. Fujii, Ph.D., K. Inagaki, Ph.D., and H. Tanaka, Ph.D. Department of Biological Resources, Faculty of Agriculture, Okayama University, Okayama, Japan. Published by Bioactive Research Institute, Okayama, Japan (1996).
In Vitro Efficacy of (Ohhira) Capsules Against Helicobacter Pylori
Authors: J. Lambert, Ph.D. and Research Assistant C. Mishra. Gastrointestinal Research , Monash University, Department of Medicine, Clayton, Victoria, Australia (1998).
The Safety of Capsules Containing (Ohhira) Lactic Acid Bacilli
Authors: T. Paraidathathu, Ph.D., and L. S. Hup, Ph.D., Pharmacy Department, Faculty of Allied Health Sciences, University of Malaysia, Kuala Lumpur, Malaysia. Symposium on Oral Recurrent Aphthous Ulcerations: Epidemiology, Clinicopathology and Management, University of Malaysia, Kuala Lumpur, Malaysia (1999).
Inhibitory Effects of (Ohhira) Lactic Acid Bacteria on Some Pathogens Including MRSA
Authors: K. Philip, Ph.D., H. Tanaka, Ph.D., and I. Ohhira, Ph.D., OMX Marketing Sdn. Bhd., Kuala Lumpur, Malaysia (1998).
The Influences on the VO; max of Athletes Taking (Ohhira) Lactic Acid Bacteria
Authors: I. Ohhira, Ph.D., M. Kawasaki, Ph.D., N. Araki, Ph.D., K. Inokihara, Ph.D., T. Matsubara, Ph.D., and H. lwasaki, Ph.D. Research conducted at Kurashiki University of Science and the Arts, Kurashiki, Japan, Research Institution of Okayama Life Science, Okayama, Japan and Sanyo Gakuen University, Okayama, Japan (1997).
Antioxidant Property and Upper Gastrointestinal Tract Conditions as Affected by (Ohhira) Probiotic Capsules.
Author: K. Philip, Ph.D., Technical Manager, OMX Marketing Sdn. Bhd., Kuala Lumpur, Malaysia (1997).
The Influences of Lactic Acid Bacteria on Bone Structure.
Authors: M. Kawakami, Ph.D., I. Ohhira, Ph.D., N. Araki, Ph.D., K. Inokihara, Ph.D., H. lwasaki, Ph.D., and T. Matsubara, Ph.D. Research conducted at Kurashiki University of Science and the Arts, Kurashiki, Japan, Research Institution of Okayama Life Science, Okayama, Japan and Sanyo Gakuen University, Okayama, Japan. (1998).
Compilation of Dental Research Papers presented at Symposium on Oral Recurrent Aphthous Ulcerations: Epidemiology, Clinicopathology and Management, University of Malaysia, Kuala Lumpur, Malaysia (1999).
Dr. Ohhira, a distinguished professor and research scientist who has lectured at universities in Malaysia, Korea, and Japan, has authored or coauthored more than 20 scientific studies on lactic acid bacteria. He has conducted research studies at Kagawa Medical College in Japan and is a respected member of the Japanese Agricultural Chemistry Association and Japanese Microbiology Association. In addition, he is a member of the New York Academy of Science and serves as the technical advisor on agricultural and environmental issues to the government of Chengda, Suchuan, China.
Awards and C.V.The Japanese Dairy and Food Association selected Dr. Ohhira's probiotics as the "Best Product" of 1991. It also received the "International Best Alternative Medicine Gold Medal" from the Euro East West Intellect at the Global Health Manille '98, a World Congress and Exposition on Integrative Heating. The Japanese Dairy and Food Association recognized Dr. Ohhira as the "Scientist of the Year" in 1991 and he is honored as being the developer of the E. faecalis TH 10 strain of bacteria.